Hypoxia-inducible factor-2 alpha promotes the proliferation of human placenta-derived mesenchymal stem cells through the MAPK/ERK signaling pathway

Human placenta-derived mesenchymal stem cells (hPMSCs) reside in a physiologically low-oxygen microenvironment. Hypoxia influences a variety of stem cell cellular activities, frequently involving hypoxia-inducible factor-2 alpha (HIF-2α). This research showed that hPMSCs cultured in hypoxic conditio...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Zhu, Chengxing, Yu, Jiong, Pan, Qiaoling, Yang, Jinfeng, Hao, Guangshu, Wang, Yingjie, Li, Lanjuan, Cao, Hongcui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073233/
https://ncbi.nlm.nih.gov/pubmed/27765951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35489
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