In vitro potency, in vitro and in vivo efficacy of liposomal alendronate in combination with γδ T cell immunotherapy in mice

Nitrogen-containing bisphosphonates (N-BP), including zoledronic acid (ZOL) and alendronate (ALD), have been proposed as sensitisers in γδ T cell immunotherapy in pre-clinical and clinical studies. Therapeutic efficacy of N-BPs is hampered by their rapid renal excretion and high affinity for bone. L...

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Vydáno v:J Control Release
Hlavní autoři: Hodgins, Naomi O., Al-Jamal, Wafa' T., Wang, Julie T-W., Parente-Pereira, Ana C., Liu, Mao, Maher, John, Al-Jamal, Khuloud T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Science Publishers 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073077/
https://ncbi.nlm.nih.gov/pubmed/27664328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.09.023
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