Maternal plasma total neopterin and kynurenine/tryptophan levels during pregnancy in relation to asthma development in the offspring

BACKGROUND: Neopterin and the kynurenine/tryptophan ratio (KTR) increases with interferon-γ stimulation, indicating Th1-immunity, and thus might be inversely associated with asthma. OBJECTIVE: To examine the association of maternal neopterin and KTR during pregnancy with asthma in the offspring. MET...

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Udgivet i:J Allergy Clin Immunol
Main Authors: Magnus, Maria C., Karlstad, Øystein, Midtun, Øivind, Håberg, Siri E., Tunheim, Gro, Parr, Christine L., Nafstad, Per, London, Stephanie J., Nilsen, Roy M., Ueland, Per M., Nystad, Wenche
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073035/
https://ncbi.nlm.nih.gov/pubmed/27221136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.02.032
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