Transcriptional regulation of the proto‐oncogene Zfp521 by SPI1 (PU.1) and HOXC13

The mouse zinc‐finger gene Zfp521 (also known as ecotropic viral insertion site 3; Evi3; and ZNF521 in humans) has been identified as a B‐cell proto‐oncogene, causing leukemia in mice following retroviral insertions in its promoter region that drive Zfp521 over‐expression. Furthermore, ZNF521 is exp...

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Detalhes bibliográficos
Publicado no:Genesis
Main Authors: Yu, Ming, Al‐Dallal, Salma, Al‐Haj, Latifa, Panjwani, Shiraj, McCartney, Akina S., Edwards, Sarah M., Manjunath, Pooja, Walker, Catherine, Awgulewitsch, Alexander, Hentges, Kathryn E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073027/
https://ncbi.nlm.nih.gov/pubmed/27506447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22963
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