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Involution of the lactating mammary gland is inhibited by the IGF system in a transgenic mouse model.

Development of the mammary gland during puberty, pregnancy, and lactation is controlled by steroid and peptide hormones and growth factors. To determine the role of the insulin-like growth factors (IGFs) in this process we developed a transgenic model using the whey acidic protein (WAP) gene to dire...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Neuenschwander, S, Schwartz, A, Wood, T L, Roberts, C T, Hennighausen, L, LeRoith, D
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1996
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507301/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8636401/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118663
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