Intravenous somatic gene transfer with antisense tissue factor restores blood flow by reducing tumor necrosis factor-induced tissue factor expression and fibrin deposition in mouse meth-A sarcoma.

Fibrin is deposited on the endothelial cell surface in the vasculature of murine methylcholanthrene A-induced sarcomas after injection of tumor necrosis factor (TNF). Capillary endothelial cells of the tumor vascular bed become positive for tissue factor after TNF injection, based on immunocytochemi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Zhang, Y., Deng, Y., Wendt, T., Liliensiek, B., Bierhaus, A., Greten, J., He, W., Chen, B., Hach-Wunderle, V., Waldherr, R., Ziegler, R., Männel, D., Stern, D. M., Nawroth, P. P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1996
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507300/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8636400/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118662
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