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Inference of gene regulation functions from dynamic transcriptome data

To quantify gene regulation, a function is required that relates transcription factor binding to DNA (input) to the rate of mRNA synthesis from a target gene (output). Such a ‘gene regulation function’ (GRF) generally cannot be measured because the experimental titration of inputs and simultaneous r...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Hillenbrand, Patrick, Maier, Kerstin C, Cramer, Patrick, Gerland, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072840/
https://ncbi.nlm.nih.gov/pubmed/27652904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12188
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