Identification of cardiac myosin peptides capable of inducing autoimmune myocarditis in BALB/c mice.

Immunization with cardiac myosin induces T cell-mediated myocarditis in genetically predisposed mice and serves as a model for autoimmune heart disease. This study was undertaken to identify pathogenic epitopes on the myosin molecule. Our approach was based on the comparison of the pathogenicity bet...

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Autors principals: Pummerer, C L, Luze, K, Grässl, G, Bachmaier, K, Offner, F, Burrell, S K, Lenz, D M, Zamborelli, T J, Penninger, J M, Neu, N
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC507280/
https://ncbi.nlm.nih.gov/pubmed/8621795
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