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Nitric oxide amplifies interleukin 1-induced cyclooxygenase-2 expression in rat mesangial cells.

Interleukin 1 and nitric oxide (NO) from infiltrating macrophages and activated mesangial cells may act in concert to sustain and promote glomerular damage. To evaluate if such synergy occurs, we evaluated the effect if IL-1 beta and NO on the formation of prostaglandin (PG)E2 and cyclooxygenase (CO...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Tetsuka, T, Daphna-Iken, D, Miller, B W, Guan, Z, Baier, L D, Morrison, A R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507279/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8621794/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118641
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