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Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody Responses

Dengue virus (DENV) is the causative agent of dengue fever and dengue hemorrhagic fever. The virus is endemic in over 120 countries, causing over 350 million infections per year. Dengue vaccine development is challenging because of the need to induce simultaneous protection against four antigenicall...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Negl Trop Dis
Prif Awduron: Metz, Stefan W., Tian, Shaomin, Hoekstra, Gabriel, Yi, Xianwen, Stone, Michelle, Horvath, Katie, Miley, Michael J., DeSimone, Joseph, Luft, Chris J., de Silva, Aravinda M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072622/
https://ncbi.nlm.nih.gov/pubmed/27764114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005071
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