c-Abl–p38α signaling plays an important role in MPTP-induced neuronal death

Oxidative stress is a major cause of sporadic Parkinson's disease (PD). Here, we demonstrated that c-Abl plays an important role in oxidative stress-induced neuronal cell death. C-Abl, a nonreceptor tyrosine kinase, was activated in an 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Wu, R, Chen, H, Ma, J, He, Q, Huang, Q, Liu, Q, Li, M, Yuan, Z
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072446/
https://ncbi.nlm.nih.gov/pubmed/26517532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.135
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