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Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain
Endoplasmic reticulum (ER) stress, defective autophagy and genomic instability in the central nervous system are often associated with severe developmental defects and neurodegeneration. Here, we reveal the role played by Rint1 in these different biological pathways to ensure normal development of t...
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Publicado no: | Cell Death Differ |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5072440/ https://ncbi.nlm.nih.gov/pubmed/26383973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.113 |
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