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Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain

Endoplasmic reticulum (ER) stress, defective autophagy and genomic instability in the central nervous system are often associated with severe developmental defects and neurodegeneration. Here, we reveal the role played by Rint1 in these different biological pathways to ensure normal development of t...

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Podrobná bibliografie
Vydáno v:Cell Death Differ
Hlavní autoři: Grigaravicius, P, Kaminska, E, Hübner, C A, McKinnon, P J, von Deimling, A, Frappart, P-O
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072440/
https://ncbi.nlm.nih.gov/pubmed/26383973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.113
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