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Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain

Endoplasmic reticulum (ER) stress, defective autophagy and genomic instability in the central nervous system are often associated with severe developmental defects and neurodegeneration. Here, we reveal the role played by Rint1 in these different biological pathways to ensure normal development of t...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Grigaravicius, P, Kaminska, E, Hübner, C A, McKinnon, P J, von Deimling, A, Frappart, P-O
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072440/
https://ncbi.nlm.nih.gov/pubmed/26383973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.113
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