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Heparan sulfation is essential for the prevention of cellular senescence
Cellular senescence is considered as an important tumor-suppressive mechanism. Here, we demonstrated that heparan sulfate (HS) prevents cellular senescence by fine-tuning of the fibroblast growth factor receptor (FGFR) signaling pathway. We found that depletion of 3′-phosphoadenosine 5′-phosphosulfa...
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| Foilsithe in: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group
2016
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5072436/ https://ncbi.nlm.nih.gov/pubmed/26250908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.107 |
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