Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells.

Rat pancreatic AR42J cells possess exocrine and neuroendocrine properties. Activin A induces morphological changes and converts them into neuron-like cells. In activin-treated cells, mRNA for pancreatic polypeptide (PP) but not that for either insulin or glucagon was detected by reverse transcriptio...

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Detalhes bibliográficos
Main Authors: Mashima, H, Ohnishi, H, Wakabayashi, K, Mine, T, Miyagawa, J, Hanafusa, T, Seno, M, Yamada, H, Kojima, I
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507229/
https://ncbi.nlm.nih.gov/pubmed/8601630
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