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Papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic.

Infection by certain human papillomavirus types is regarded as the major risk factor in the development of cervical cancer, one of the most common cancers of women worldwide. Analysis of the immunogenic and structural features of papillomavirus virions has been hampered by the inability to efficient...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kirnbauer, R, Booy, F, Cheng, N, Lowy, D R, Schiller, J T
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50722/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1334560/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.24.12180
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