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Presence of hypochlorite-modified proteins in human atherosclerotic lesions.

Oxidation of LDL may contribute to atherogenesis, though the nature of the in vivo oxidant(s) remains obscure. Myeloperoxidase, the enzyme responsible for hypochlorous acid/hypochlorite (HOCl) production in vivo, is present in active form in human atherosclerotic lesions, and HOCl aggregates and tra...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Hazell, L J, Arnold, L, Flowers, D, Waeg, G, Malle, E, Stocker, R
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507214/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8617887/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118576
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