AKT/GSK3β signaling pathway is critically involved in human pluripotent stem cell survival

Human embryonic and induced pluripotent stem cells are self-renewing pluripotent stem cells (PSC) that can differentiate into a wide range of specialized cells. Basic fibroblast growth factor is essential for PSC survival, stemness and self-renewal. PI3K/AKT pathway regulates cell viability and apop...

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Udgivet i:Sci Rep
Main Authors: Romorini, Leonardo, Garate, Ximena, Neiman, Gabriel, Luzzani, Carlos, Furmento, Verónica Alejandra, Guberman, Alejandra Sonia, Sevlever, Gustavo Emilio, Scassa, María Elida, Miriuka, Santiago Gabriel
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071844/
https://ncbi.nlm.nih.gov/pubmed/27762303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35660
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