Suppression of cell-mediated and humoral immune responses by an interleukin-2-immunoglobulin fusion protein in mice.

Interleukin-2 (IL-2) plays a pivotal role in the cellular and humoral immune responses directed against foreign antigens. We characterized the in vitro and in vivo properties of a chimeric protein consisting of mouse IL-2 fused to the mouse IgG2b Fc domains. This fusion protein binds to IL-2 and Fc...

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Detalhes bibliográficos
Main Authors: Kunzendorf, U, Pohl, T, Bulfone-Paus, S, Krause, H, Notter, M, Onu, A, Walz, G, Diamantstein, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507172/
https://ncbi.nlm.nih.gov/pubmed/8636431
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