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Active and adaptive Legionella CRISPR‐Cas reveals a recurrent challenge to the pathogen

Clustered regularly interspaced short palindromic repeats with CRISPR‐associated gene (CRISPR‐Cas) systems are widely recognized as critical genome defense systems that protect microbes from external threats such as bacteriophage infection. Several isolates of the intracellular pathogen Legionella p...

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Detalhes bibliográficos
Publicado no:Cell Microbiol
Main Authors: Rao, Chitong, Guyard, Cyril, Pelaz, Carmen, Wasserscheid, Jessica, Bondy‐Denomy, Joseph, Dewar, Ken, Ensminger, Alexander W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071653/
https://ncbi.nlm.nih.gov/pubmed/26936325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12586
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