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A high-throughput screening assay for eukaryotic elongation factor 2 kinase inhibitors

Eukaryotic elongation factor 2 kinase (eEF2K) inhibitors may aid in the development of new therapeutic agents to combat cancer. Purified human eEF2K was obtained from an Escherichia coli expression system and a luminescence-based high-throughput screening (HTS) assay was developed using MH-1 peptide...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Xiao, Ting, Liu, Rui, Proud, Christopher G., Wang, Ming-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071636/
https://ncbi.nlm.nih.gov/pubmed/27818922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2016.04.002
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