In vivo neutralization of eosinophil-derived major basic protein inhibits antigen-induced bronchial hyperreactivity in sensitized guinea pigs.

This study examines the effect of purified rabbit antiguinea pig eosinophil-derived major basic protein (MBP) Ig on antigen-induced bronchial hyperreactivity to inhaled acetylcholine in aerosol-sensitized guinea pigs. Ovalbumin inhalation by sensitized guinea pigs induced a rise in the numbers of eo...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Lefort, J, Nahori, M A, Ruffie, C, Vargaftig, B B, Pretolani, M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8613536/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118505
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