Augmented oxidative stress and preserved vasoconstriction induced by hydrogen peroxide in coronary arteries in obesity: role of COX‐2

BACKGROUND AND PURPOSE: Oxidative stress plays a key role in the vascular and metabolic abnormalities associated with obesity. Herein, we assessed whether obesity can increase coronary vasoconstriction induced by hydrogen peroxide (H(2)O(2)) and the signalling pathways involving COX‐2 and superoxide...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Santiago, Elvira, Martínez, Maria Pilar, Climent, Belén, Muñoz, Mercedes, Briones, Ana María, Salaices, Mercedes, García‐Sacristán, Albino, Rivera, Luis, Prieto, Dolores
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071563/
https://ncbi.nlm.nih.gov/pubmed/27535007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13579
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