RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells

RUNX1 is a transcription factor functioning both as an oncogene and a tumor suppressor in breast cancer. RUNX1 alters chromatin structure in cooperation with chromatin modifier and remodeling enzymes. In this study, we examined the relationship between RUNX1-mediated transcription and genome organiz...

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Publicado no:Biochim Biophys Acta
Main Authors: Barutcu, A. Rasim, Hong, Deli, Lajoie, Bryan R., McCord, Rachel Patton, van Wijnen, Andre J., Lian, Jane B., Stein, Janet L., Dekker, Job, Imbalzano, Anthony N., Stein, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071180/
https://ncbi.nlm.nih.gov/pubmed/27514584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2016.08.003
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