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Pancytopenia and Severe Gastrointestinal Toxicities Associated with 5-Fluorouracil in a Patient with Thymidylate Synthase (TYMS) Polymorphism

5-Fluorouracil (5-FU) is one of the most commonly used chemotherapeutic agents in solid tumors, including colon, gastric and breast cancers. The pharmacogenetic syndrome of dihydropyrimidine dehydrogenase (DPD) deficiency leading to severe toxicity after administration of 5-flourouracil (5-FU) and c...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cureus
मुख्य लेखकों: Wang, Bo, Walsh, Shannon J, Saif, Muhammad W
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cureus 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071174/
https://ncbi.nlm.nih.gov/pubmed/27774364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7759/cureus.798
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