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Pancytopenia and Severe Gastrointestinal Toxicities Associated with 5-Fluorouracil in a Patient with Thymidylate Synthase (TYMS) Polymorphism
5-Fluorouracil (5-FU) is one of the most commonly used chemotherapeutic agents in solid tumors, including colon, gastric and breast cancers. The pharmacogenetic syndrome of dihydropyrimidine dehydrogenase (DPD) deficiency leading to severe toxicity after administration of 5-flourouracil (5-FU) and c...
में बचाया:
में प्रकाशित: | Cureus |
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मुख्य लेखकों: | , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Cureus
2016
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5071174/ https://ncbi.nlm.nih.gov/pubmed/27774364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7759/cureus.798 |
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