Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations

Obesity-related insulin resistance is associated with fatty liver, dyslipidemia, and low plasma adiponectin. Insulin resistance due to insulin receptor (INSR) dysfunction is associated with none of these, but when due to dysfunction of the downstream kinase AKT2 phenocopies obesity-related insulin r...

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書誌詳細
出版年:JCI Insight
主要な著者: Huang-Doran, Isabel, Tomlinson, Patsy, Payne, Felicity, Gast, Alexandra, Sleigh, Alison, Bottomley, William, Harris, Julie, Daly, Allan, Rocha, Nuno, Rudge, Simon, Clark, Jonathan, Kwok, Albert, Romeo, Stefano, McCann, Emma, Müksch, Barbara, Dattani, Mehul, Zucchini, Stefano, Wakelam, Michael, Foukas, Lazaros C., Savage, David B., Murphy, Rinki, O’Rahilly, Stephen, Barroso, Inês, Semple, Robert K.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2016
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070960/
https://ncbi.nlm.nih.gov/pubmed/27766312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88766
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