IP(3) receptors regulate vascular smooth muscle contractility and hypertension

Inositol 1, 4, 5-trisphosphate receptor–mediated (IP(3)R-mediated) calcium (Ca(2+)) release has been proposed to play an important role in regulating vascular smooth muscle cell (VSMC) contraction for decades. However, whether and how IP(3)R regulates blood pressure in vivo remains unclear. To addre...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Lin, Qingsong, Zhao, Guiling, Fang, Xi, Peng, Xiaohong, Tang, Huayuan, Wang, Hong, Jing, Ran, Liu, Jie, Lederer, W. Jonathan, Chen, Ju, Ouyang, Kunfu
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070959/
https://ncbi.nlm.nih.gov/pubmed/27777977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89402
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