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Acquired resistance to innate immune clearance promotes Klebsiella pneumoniae ST258 pulmonary infection

Adaptive changes in the genome of a locally predominant clinical isolate of the multidrug-resistant Klebsiella pneumoniae ST258 (KP35) were identified and help to explain the selection of this strain as a successful pulmonary pathogen. The acquisition of 4 new ortholog groups, including an arginine...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Ahn, Danielle, Peñaloza, Hernán, Wang, Zheng, Wickersham, Matthew, Parker, Dane, Patel, Purvi, Koller, Antonius, Chen, Emily I., Bueno, Susan M., Uhlemann, Anne-Catrin, Prince, Alice
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070956/
https://ncbi.nlm.nih.gov/pubmed/27777978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89704
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