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Intramuscular Neurotrophin-3 normalizes low threshold spinal reflexes, reduces spasms and improves mobility after bilateral corticospinal tract injury in rats

Brain and spinal injury reduce mobility and often impair sensorimotor processing in the spinal cord leading to spasticity. Here, we establish that complete transection of corticospinal pathways in the pyramids impairs locomotion and leads to increased spasms and excessive mono- and polysynaptic low...

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Pubblicato in:eLife
Autori principali: Kathe, Claudia, Hutson, Thomas Haynes, McMahon, Stephen Brendan, Moon, Lawrence David Falcon
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070949/
https://ncbi.nlm.nih.gov/pubmed/27759565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18146
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