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Common coding variants in the HLA-DQB1 region confer susceptibility to age-related macular degeneration

Age-related macular degeneration (AMD) risk variants in the complement system point to the important role of immune response and inflammation in the pathogenesis of AMD. Although the human leukocyte antigen (HLA) region has a central role in regulating immune response, previous studies of genetic va...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Jorgenson, Eric, Melles, Ronald B, Hoffmann, Thomas J, Jia, Xiaoming, Sakoda, Lori C, Kvale, Mark N, Banda, Yambazi, Schaefer, Catherine, Risch, Neil, Shen, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070898/
https://ncbi.nlm.nih.gov/pubmed/26733291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.247
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