Human diabetes associated with defects in nuclear regulatory proteins for the insulin receptor gene.
The control of gene transcription is mediated by sequence-specific DNA-binding proteins (trans-acting factors) that bind to upstream regulatory elements (cis elements). We have previously identified two DNA-binding proteins that specifically interact with two unique AT-rich sequences of the 5' regul...
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| Veröffentlicht in: | J Clin Invest |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
1996
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507088/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8550844/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118400 |
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