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Human diabetes associated with defects in nuclear regulatory proteins for the insulin receptor gene.

The control of gene transcription is mediated by sequence-specific DNA-binding proteins (trans-acting factors) that bind to upstream regulatory elements (cis elements). We have previously identified two DNA-binding proteins that specifically interact with two unique AT-rich sequences of the 5' regul...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Brunetti, A, Brunetti, L, Foti, D, Accili, D, Goldfine, I D
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1996
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507088/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8550844/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118400
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