Protective Efficacy of Plasmodium vivax Radiation-Attenuated Sporozoites in Colombian Volunteers: A Randomized Controlled Trial

BACKGROUND: Immunizing human volunteers by mosquito bite with radiation-attenuated Plasmodium falciparum sporozoites (RAS) results in high-level protection against infection. Only two volunteers have been similarly immunized with P. vivax (Pv) RAS, and both were protected. A phase 2 controlled clini...

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Veröffentlicht in:PLoS Negl Trop Dis
Hauptverfasser: Arévalo-Herrera, Myriam, Vásquez-Jiménez, Juan M., Lopez-Perez, Mary, Vallejo, Andrés F., Amado-Garavito, Andrés B., Céspedes, Nora, Castellanos, Angélica, Molina, Karen, Trejos, Johanna, Oñate, José, Epstein, Judith E., Richie, Thomas L., Herrera, Sócrates
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070852/
https://ncbi.nlm.nih.gov/pubmed/27760143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005070
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