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TLR2 activation limits rhinovirus-stimulated CXCL-10 by attenuating IRAK-1-dependent IL-33 receptor signaling in human bronchial epithelial cells

Airway epithelial cells are the major target for rhinovirus (RV) infection and express pro-inflammatory chemokines and antiviral cytokines that play a role in innate immunity. Previously, we demonstrated that RV interaction with TLR2 causes IRAK-1 depletion in both airway epithelial cells and macrop...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Ganesan, Shyamala, Pham, Duc, Jing, Yaxun, Farazuddin, Mohammad, Hudy, Magdalena H., Unger, Benjamin, Comstock, Adam T, Proud, David, Lauring, Adam S., Sajjan, Uma S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070654/
https://ncbi.nlm.nih.gov/pubmed/27503209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502702
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