GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer

BACKGROUND AND AIMS: The role of GATA factors in cancer has gained increasing attention recently, but the function of GATA6 in pancreatic ductal adenocarcinoma (PDAC) is controversial. GATA6 is amplified in a subset of tumours and was proposed to be oncogenic, but high GATA6 levels are found in well...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Martinelli, Paola, Carrillo-de Santa Pau, Enrique, Cox, Trevor, Sainz, Bruno, Dusetti, Nelson, Greenhalf, William, Rinaldi, Lorenzo, Costello, Eithne, Ghaneh, Paula, Malats, Núria, Büchler, Markus, Pajic, Marina, Biankin, Andrew V, Iovanna, Juan, Neoptolemos, John, Real, Francisco X
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Pancreas
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070637/
https://ncbi.nlm.nih.gov/pubmed/27325420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2015-311256
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