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What do we learn from the murine Jacob/Nsmf gene knockout for human disease?

Mutations in the NSMF gene have been related to Kallmann syndrome. Conflicting results have been reported on the subcellular localization of Jacob/NELF, the protein encoded by the NSMF gene. Some reports indicate an extracellular localization and a function as a guidance molecule for migration of Gn...

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Detalhes bibliográficos
Publicado no:Rare Dis
Main Authors: Spilker, Christina, Grochowska, Katarzyna M., Kreutz, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070631/
https://ncbi.nlm.nih.gov/pubmed/27803842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21675511.2016.1241361
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