The feasibility of incorporating Vpx into lentiviral gene therapy vectors

While current antiretroviral therapy has significantly improved, challenges still remain in life-long targeting of HIV-1 reservoirs. Lentiviral gene therapy has the potential to deliver protective genes into the HIV-1 reservoir. However, inefficient reverse transcription (RT) occurs in HIV-1 reservo...

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Bibliographic Details
Published in:Mol Ther Methods Clin Dev
Main Authors: McAllery, Samantha A, Ahlenstiel, Chantelle L, Suzuki, Kazuo, Symonds, Geoff P, Kelleher, Anthony D, Turville, Stuart G
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070512/
https://ncbi.nlm.nih.gov/pubmed/27790625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.66
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