Autophagy Improves the Immunosuppression of CD4(+) T Cells by Mesenchymal Stem Cells Through Transforming Growth Factor-β1

Mesenchymal stem cells (MSCs) have been extensively investigated as a promising approach to treat many autoimmune and inflammatory diseases. The stress condition would affect the therapeutic efficacy and induce autophagy of MSCs. However, whether autophagy would affect the immunosuppressive capacity...

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Bibliographic Details
Published in:Stem Cells Transl Med
Main Authors: Gao, Liangbin, Cen, Shuizhong, Wang, Peng, Xie, Zhongyu, Liu, Zhenhua, Deng, Wen, Su, Hongjun, Wu, Xiaohua, Wang, Shan, Li, Jinteng, Ouyang, Yi, Wu, Yanfeng, Shen, Huiyong
Format: Artigo
Language:Inglês
Published: AlphaMed Press 2016
Subjects:
Cell-Based Drug Development, Screening, and Toxicology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070508/
https://ncbi.nlm.nih.gov/pubmed/27400793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0420
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