Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation.

The period of hypoxia is an important priming event for the vascular dysfunction that accompanies reperfusion, with endothelial cells (ECs) and neutrophils (PMNs) playing a central role. We hypothesized that EC Weibel-Palade (WP) body exocytosis during the hypoxic/ischemic period during organ preser...

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Publié dans:	J Clin Invest
Auteurs principaux:	Pinsky, D J, Naka, Y, Liao, H, Oz, M C, Wagner, D D, Mayadas, T N, Johnson, R C, Hynes, R O, Heath, M, Lawson, C A, Stern, D M
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507042/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8567972/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118440
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