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Rapid Exchange Between Free and Bound States in RNA-Dendrimer Polyplexes: Implications on the Mechanism of Delivery and Release

A combination of solution NMR, dynamic light scattering (DLS), and fluorescence quenching assays were employed to obtain insights into the dynamics and structural features of a polyplex system consisting of HIV-1 transactivation response element (TAR) and PEGylated generation 5 poly(amidoamine) dend...

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Detalhes bibliográficos
Publicado no:Biomacromolecules
Main Authors: Shakya, Anisha, Dougherty, Casey A., Xue, Yi, Al-Hashimi, Hashim M., Banaszak Holl, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070374/
https://ncbi.nlm.nih.gov/pubmed/26595195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.5b01280
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