Bone Morphogenic Protein Type 2 Receptor Mutation-Independent Mechanisms of Disrupted Bone Morphogenetic Protein Signaling in Idiopathic Pulmonary Arterial Hypertension

Altered bone morphogenic protein (BMP) signaling, independent of BMPR2 mutations, can result in idiopathic pulmonary arterial hypertension (IPAH). Glucose dysregulation can regulate multiple processes in IPAH. However, the role of glucose in BMP antagonist expression in IPAH has not been characteriz...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Barnes, Jarrod W., Kucera, Elif T., Tian, Liping, Mellor, Noël E., Dvorina, Nina, Baldwin, William W., Aldred, Micheala A., Farver, Carol F., Comhair, Suzy A. A., Aytekin, Metin, Dweik, Raed A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070111/
https://ncbi.nlm.nih.gov/pubmed/27187737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0402OC
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