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Ascorbic Acid Attenuates Hyperoxia-Compromised Host Defense against Pulmonary Bacterial Infection

Supraphysiological concentrations of oxygen (hyperoxia) can compromise host defense and increase susceptibility to bacterial infections, causing ventilator-associated pneumonia. The phagocytic activity of macrophages is impaired by hyperoxia-induced increases in the levels of reactive oxygen species...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Patel, Vivek S., Sampat, Vaishali, Espey, Michael Graham, Sitapara, Ravikumar, Wang, Haichao, Yang, Xiaojing, Ashby, Charles R., Thomas, Douglas D., Mantell, Lin L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070105/
https://ncbi.nlm.nih.gov/pubmed/27120084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0310OC
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