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RARγ-induced E-cadherin downregulation promotes hepatocellular carcinoma invasion and metastasis

BACKGROUND: Aberrant expression of Retinoic acid receptor γ (RARγ) is implicated in cancer development. Our previous study identified that RARγ functions as a tumor promoter to drive hepatocellular carcinoma (HCC) growth. However, its contribution to HCC invasion and metastasis remains unclear. METH...

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Podrobná bibliografie
Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Gan, Wen-Juan, Wang, Jing-Ru, Zhu, Xiao-Li, He, Xiao-Shun, Guo, Peng-Da, Zhang, Shen, Li, Xiu-Ming, Li, Jian-Ming, Wu, Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069892/
https://ncbi.nlm.nih.gov/pubmed/27756432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0441-9
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