Drug discovery using clinical outcome-based Connectivity Mapping: application to ovarian cancer

BACKGROUND: Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer death among women in the United States (5 % of cancer deaths). The standard treatment for patients with advanced EOC is initial debulking surgery followed by carboplatin-paclitaxel combination chemotherapy. Unfortunatel...

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Pubblicato in:BMC Genomics
Autori principali: Raghavan, Rama, Hyter, Stephen, Pathak, Harsh B., Godwin, Andrew K., Konecny, Gottfried, Wang, Chen, Goode, Ellen L., Fridley, Brooke L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069875/
https://ncbi.nlm.nih.gov/pubmed/27756228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3149-5
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