Hepatocellular carcinoma-targeted drug discovery through image-based phenotypic screening in co-cultures of HCC cells with hepatocytes

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common malignant cancers worldwide and is associated with substantial mortality. Because HCCs have strong resistance to conventional chemotherapeutic agents, novel therapeutic strategies are needed to improve survival in HCC patients. MET...

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Publicado en:BMC Cancer
Autores principales: Jang, Jae-Woo, Song, Yeonhwa, Kim, Kang Mo, Kim, Jin-Sun, Choi, Eun Kyung, Kim, Joon, Seo, Haengran
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069815/
https://ncbi.nlm.nih.gov/pubmed/27756242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2816-x
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