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Size polymorphism and low sequence diversity in the locus encoding the Plasmodium vivax rhoptry neck protein 4 (PvRON4) in Colombian isolates

BACKGROUND: Designing a vaccine against Plasmodium vivax has focused on selecting antigens involved in invasion mechanisms that must have domains with low polymorphism for avoiding allele-specific immune responses. The rhoptry neck protein 4 (RON4) forms part of the tight junction, which is essentia...

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Bibliographische Detailangaben
Veröffentlicht in:Malar J
Hauptverfasser: Buitrago, Sindy P., Garzón-Ospina, Diego, Patarroyo, Manuel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069803/
https://ncbi.nlm.nih.gov/pubmed/27756311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1563-4
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