A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of 2 and 4 Weeks of Twice-Daily Ocular Trabodenoson in Adults with Ocular Hypertension or Primary Open-Angle Glaucoma

Purpose: To evaluate the safety and ocular hypotensive efficacy of 4 trabodenoson doses administered twice daily over 14 or 28 days in subjects with ocular hypertension or primary open-angle glaucoma (POAG). Methods: In this multicenter, randomized, double-masked, placebo-controlled, dose-escalation...

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Detalhes bibliográficos
Publicado no:J Ocul Pharmacol Ther
Main Authors: Myers, Jonathan S., Sall, Kenneth N., DuBiner, Harvey, Slomowitz, Natanya, McVicar, William, Rich, Cadmus C., Baumgartner, Rudolf A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069706/
https://ncbi.nlm.nih.gov/pubmed/27002298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2015.0148
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