Genome-wide profiling of the human papillomavirus DNA integration in cervical intraepithelial neoplasia and normal cervical epithelium by HPV capture technology

HPV integration plays an important role in cervical carcinogenesis. HPV genotypes and the exact integration sites were investigated using HPV capture technology combined with next generation sequencing in 166 women. Three, one and six integration sites were verified in 7 HPV-positive ‘normal cervica...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Ying, Zhang, Chaoting, Gao, Weijiao, Wang, Limin, Pan, Yaqi, Gao, Yunong, Lu, Zheming, Ke, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069689/
https://ncbi.nlm.nih.gov/pubmed/27759101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35427
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