A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells

Circulating tumor cells (CTCs) were introduced as biomarkers more than 10 years ago, but capture of viable CTCs at high purity from peripheral blood of cancer patients is still a major technical challenge. Here, we report a novel microfluidic platform designed for marker independent capture of CTCs....

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Hvichia, G.E., Parveen, Z., Wagner, C., Janning, M., Quidde, J., Stein, A., Müller, V., Loges, S., Neves, R.P.L., Stoecklein, N.H., Wikman, H., Riethdorf, S., Pantel, K., Gorges, T.M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Cancer Genetics and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069649/
https://ncbi.nlm.nih.gov/pubmed/26789903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30007
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