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Adaptive Immunity Is the Primary Force Driving Selection of Equine Infectious Anemia Virus Envelope SU Variants during Acute Infection

Equine infectious anemia virus (EIAV) is a lentivirus that causes persistent infection in horses. The appearance of antigenically distinct viral variants during recurrent viremic episodes is thought to be due to adaptive immune selection pressure. To test this hypothesis, we evaluated envelope SU cl...

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Bibliografiske detaljer
Main Authors: Mealey, Robert H., Leib, Steven R., Pownder, Sarah L., McGuire, Travis C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC506964/
https://ncbi.nlm.nih.gov/pubmed/15308724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.17.9295-9305.2004
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