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The Effect of a High‐Fat Meal on the Pharmacokinetics of Ixazomib, an Oral Proteasome Inhibitor, in Patients With Advanced Solid Tumors or Lymphoma

Ixazomib is the first oral proteasome inhibitor to be investigated in the clinic. This clinical study assessed whether the pharmacokinetics of ixazomib would be altered if administered after a high‐calorie, high‐fat meal. In a 2‐period, 2‐sequence, crossover study design, adult patients with advance...

詳細記述

保存先:
書誌詳細
出版年:J Clin Pharmacol
主要な著者: Gupta, Neeraj, Hanley, Michael J., Venkatakrishnan, Karthik, Wang, Bingxia, Sharma, Sunil, Bessudo, Alberto, Hui, Ai‐Min, Nemunaitis, John
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069578/
https://ncbi.nlm.nih.gov/pubmed/26872892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.719
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