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Neonatal cardiac dysfunction and transcriptome changes caused by the absence of Celf1
The RNA binding protein Celf1 regulates alternative splicing in the nucleus and mRNA stability and translation in the cytoplasm. Celf1 is strongly down-regulated during mouse postnatal heart development. Its re-induction in adults induced severe heart failure and reversion to fetal splicing and gene...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5069560/ https://ncbi.nlm.nih.gov/pubmed/27759042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35550 |
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